Lead revision surgery for vagus nerve stimulation in epilepsy: Outcomes and efficacy.

Epilepsy Behav. 2014 Jan 2;31C:110-113. doi: 10.1016/j.yebeh.2013.12.002. [Epub ahead of print]

Lead revision surgery for vagus nerve stimulation in epilepsy: Outcomes and efficacy.

Waseem H¹, Raffa SJ², Benbadis SR³, Vale FL⁴.

Author information

• ¹Department of Neurosurgery and Brain Repair, Morsani College of Medicine, University of South Florida, 2 Tampa General Circle, USF Health, 7th Floor, Tampa, FL 33606, USA. Electronic address: hwaseem@health.usf.edu.
• ²Department of Neurosurgery and Brain Repair, Morsani College of Medicine, University of South Florida, 2 Tampa General Circle, USF Health, 7th Floor, Tampa, FL 33606, USA. Electronic address: sraffa@health.usf.edu.
• ³Department of Neurology, Morsani College of Medicine, University of South Florida, 2 Tampa General Circle, USF Health, 6th Floor, Tampa, FL 33606, USA. Electronic address: sbenbadi@health.usf.edu.
• ⁴Department of Neurosurgery and Brain Repair, Morsani College of Medicine, University of South Florida, 2 Tampa General Circle, USF Health, 7th Floor, Tampa, FL 33606, USA. Electronic address: fvale@health.usf.edu.

Abstract

We present, to our knowledge, the first published analysis of vagus nerve stimulation (VNS) lead revisions to incorporate quality of life, clinical response, and antiepileptic drug (AED) burden in postrevision clinical outcomes. Ten patients were followed and had no postoperative complications. Seven patients had improvement in quality of life, and three experienced no change. Eight patients noted a restoration of clinical response comparable with initial VNS implantation. Seven patients reported 30-60% improvement in seizure reduction, two experienced >60%, and one noted <30%. Six patients had no change in AED burden. Vagus nerve stimulation lead revision should be considered a safe option for patients with VNS lead failure and medically intractable epilepsy.

Copyright © 2013 Elsevier Inc. All rights reserved.

KEYWORDS:

AED, Epilepsy surgery, Intractable epilepsy, Lead revision, Seizure disorder, VNS, Vagus nerve stimulation, antiepileptic drug, vagus nerve stimulation

PMID:

24389021

[PubMed - as supplied by publisher]

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Lead revision surgery for vagus nerve stimulation in epilepsy: Outcomes and effi...

• Lead revision surgery for vagus nerve stimulation in epilepsy: Outcomes and efficacy.

  Epilepsy Behav. 2014 Jan 2;31C:110-113. doi: 10.1016/j.yebeh.2013.12.002. [Epub ahead of print]

  PubMed

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http://www.ncbi.nlm.nih.gov/pubmed/24389021